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Instead, your levels may rise due to: taking too many supplements or taking them for too long having liver conditions that challenge excretion, like alcoholic liver disease, cirrhosis, or hepatitis having kidney disease A 2021 article notes that too much oral or injected vitamin B12 is not associated with any significant side effects or harm

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B12 levels can become low as a result of inadequate nutrition, decreased absorption of this vitamin in the intestines, stomach problems, infections or cancer